Every day, the human body harnesses the power of light through a series of intricate photochemical reactions. From the photosensitive cells that enable our vision to the synthesis of vitamin D in our skin, light plays an indispensable role in our physiological processes. Given this intimate relationship between light and cellular activity, one naturally wonders: how might other cells in our body respond to light, and can we leverage this response for therapeutic purposes? Enter Low-Level Laser Therapy (LLLT) – also known as Cold Laser Therapy or Photobiomodulation (PBM) Therapy – a groundbreaking treatment method that delves into the fascinating intersection of light and cellular health.
What Is Low-Level Laser Therapy (LLLT)?
Discovered in 1967 by Endre Mester, Low-Level Laser Therapy involves placing a low-power laser near to or on the skin, allowing the photons to move through the tissue and interact with cells in the body.
A Low-Level Laser can be roughly categorised as having a power output of less than 500mW, and is classified by the FDA as either ‘Class IIIB Lasers’, ‘Class IIIR Lasers’, or ‘Class II Lasers’ (i.e. low risk of hazard).
Various dosimetry parameters (e.g. wavelength, fluence, power density) are used depending on the device / treatment type, with different wavelengths commonly referred to as red light therapy, green light therapy, or violet light therapy, each producing distinct biological effects within tissue.
What Are the Benefits of Low-Level Laser Therapy (LLLT) and How Does It Work?
Since the development of the procedure, the benefits of Low-Level Laser Therapy have been studied at length – the photochemical changes that occur in cells as a reaction to the application of light can help in many ways, including:
- Pain Management
Pain is the most common reason that people see doctors, with roughly one in ten people affected by high-impact chronic pain each year. LLLT has been explored in clinical studies as a way of decreasing several types of pain, including:
• Orthopaedic pain: LLLT has pain-reducing effects on musculoskeletal conditions such as those experienced by patients recovering from sprains, whiplash, muscular pain, cervical or lumbar radiculopathy, tendinitis, and carpal tunnel syndrome. LLLT has also shown positive effects on individuals with chronic conditions like arthritis and osteoarthritis, and in treating post-surgical dental pain.
• Neuropathic pain: Neuropathic pain conditions can be treated effectively with LLLT, including various types of neuralgia and diabetic neuropathy.
Although we still have a lot to learn about the effects of light energy on different types of cells, the leading theory is that Low-Level Laser Therapy generates therapeutic effects through stimulating and enhancing specific biochemical processes. Intuitively speaking, laser energy activates a key enzyme in our cells’ powerhouses (mitochondria), boosting energy production and cellular activity. This process enhances cell function, aids in cell repair and growth, and supports overall cellular health, leading to improved healing and regeneration.
More specifically, utilising the first law in photochemistry (Grotthuss-Draper law), laser energy is transferred to cytochrome c oxidase (CcO) – a respiratory energy-transducing enzyme which is involved in the electron transport chain in mitochondria. This energy transfer causes photodissociation of inhibitory nitric oxide from CcO, leading to an enhancement of enzyme activity, electron transport, mitochondrial respiration, and adenosine triphosphate (ATP) production. Consequently, by altering the cellular redox state, LLLT induces the activation of numerous intracellular signalling pathways, and alters the affinity of transcription factors concerned with cell proliferation, survival, repair, and regeneration.
- Fat Removal
Multiple studies have been conducted to determine whether Low-Level Laser Therapy can be used for fat reduction, with positive results. One review found that LLLT is effective at reducing fat and cellulite and improves blood lipid profiles with little to no side effects.
The current theory as to why LLLT is effective for fat loss is that it creates transient pores in adipocytes (fat cells), allowing lipids (fatty liquids) to leak out. The fatty liquids are then naturally flushed out through the lymphatic system.
The result is that the fat cells shrink instead of being killed. When this happens, the shrunken fat cells begin to act and function like healthy lean cells, releasing the correct messages to the brain and creating a communication effect throughout the fat organ, causing other fat cells to release their content and return their hormone responses to the positive.
Procedures that have been popular in the past (such as fat freezing) focus on the elimination of fat cells, but recent research on LLLT for body sculpting has shown this approach to be less effective, and in the worst-case scenario, providing counterproductive results.
- Fungal Nail Treatment
The unsightly onychomycosis is a fungal infection of the nails that causes discoloration, thickening, and separation from the nail bed. Onychomycosis is a very common condition, occurring in approximately 10% of the general population, with those over 60 being especially affected (20% – 50%).
The most common treatments for fungal nail infections include antifungal nail creams (largely ineffective) and prescription antifungal medications taken orally (can cause side effects). LLLT has been shown to effectively treat nail fungus with little to no side effects.
Although the exact mechanism of action is currently unclear, it is theorised that Low-Level Laser Therapy triggers a photochemical reaction, producing Reactive Oxygen Species (ROS) which is converted to Hydrogen Peroxide – a natural antiseptic that kills onychomycosis. In addition, LLLT induces the production of Adenosine Triphosphate (ATP) which is converted to Nitric Oxide, aiding the natural immune response in fighting the infection.
- Hair Regrowth
LLLT has shown promising results in the treatment of hair loss. Low-Level Laser Therapy is often used to address various forms of hair thinning and baldness, such as androgenetic alopecia (pattern baldness) and telogen effluvium (temporary hair shedding).
The primary mechanism behind LLLT for hair loss involves the absorption of laser light by the cells in the hair follicles. This light energy is believed to trigger the release of nitric oxide, which improves vascularization and oxygen supply to the follicles. Additionally, LLLT can increase the levels of ATP in follicular cells, providing them with the necessary energy to grow thicker, healthier hair.
While more research is needed to fully understand the extent of LLLT’s benefits for different types of hair loss, current studies and clinical trials indicate that it is a safe and effective option for those seeking to improve their hair growth and density.
What Are the Side Effects of Low-Level Laser Therapy (LLLT) and Is It Safe?
LLLT is widely regarded as a safe treatment choice, particularly when conducted under the expert guidance of medical professionals. The non-invasive nature of the therapy and its avoidance of high heat reduce the risk of complications, affirming its safety profile. Regulatory bodies such as the FDA categorise LLLT devices as low-risk, further validating their safety for therapeutic use.
Despite its well-documented benefits and robust safety record, Low-Level Laser Therapy may cause minor side effects, such as temporary discomfort at the treatment site, mild skin irritation, or occasionally, an increase in pain or swelling immediately post-treatment. These symptoms are generally transient and resolve on their own.
Overall, the low incidence of side effects makes LLLT a compelling option for the management of various conditions, underscoring its effectiveness and safety.
What Is the Cost of Low-Level Laser Therapy (LLLT) and How Successful Is It?
The cost of Low-Level Laser Therapy varies based on several factors. While treatments are typically short, lasting from 60 seconds to 10 minutes, the price per session can range from $50 to $150, depending on the clinic, the type of device, and the complexity of the treatment area.
Additionally, the total cost for a patient depends on the number of sessions required. Some conditions may only need three sessions, with a total cost of around $150. However, more complex issues may require up to 30 sessions, potentially bringing the total to nearly $2,000.
Low-Level Laser Therapy is an advanced therapy that requires specialised technology and professional expertise, which contributes to its overall cost. However, as a non-invasive treatment that effectively manages various medical conditions, LLLT represents a valuable investment in long-term health.
Low-Level Laser Therapy has shown varying success rates depending on the condition being treated, the protocol used, and individual patient responses. For instance:
- Hair Growth: Studies have shown that LLLT can be effective in promoting hair growth in individuals with androgenetic alopecia. For example, Barikbin et al. reported a substantial increase in terminal hair density using LLLT devices, with increases of up to 9.61/cm². Mai-Yi Fan et al. found that LLLT significantly improved hair coverage, thickness, and count compared to sham devices. Similarly, Suchonwanit et al. observed a 51% increase in terminal hair counts and notable improvements in hair diameter using LLLT. Jimenez et al. confirmed the effectiveness of LLLT in enhancing hair density for both male and female patients.
- Pain Management: Research consistently demonstrates the efficacy of LLLT in treating various types of pain. For instance, a meta-analysis by Fulop et al. reviewed 22 studies and revealed significant positive effects of LLLT on pain relief. Similarly, a systematic review and meta-analysis by Chow et al. found that LLLT provided immediate pain relief and sustained benefits for up to 22 weeks post-treatment in chronic neck pain sufferers. Additionally, studies by Gur et al. reported significant pain reduction and improved function in fibromyalgia patients treated with LLLT.
- Wound Healing: LLLT has shown considerable success in enhancing wound healing. For instance, Yildiz MS et al. found that the percentage of complete wound epithelialization (CWE) was significantly higher in LLLT-treated groups by the 14th day post-surgery, suggesting faster and more effective healing. Additionally, studies indicate that the extent of wound epithelialization, measured by stained surface areas, is consistently lower in LLLT-treated groups compared to control groups. For example, Heidari M et al. reported significant improvements in wound healing at donor sites with the use of LLLT.
It is important to note that individual responses can vary based on factors such as the severity of the condition, the treatment regimen, and the specific device used.
What Is the Difference Between Low-Level Laser Therapy (LLLT) and High-Level Laser Therapy (HLLT)?
To understand the difference between High-Level Laser Therapy (HLLT – also known as High-Power Laser Therapy or High-Intensity Laser Therapy) and Low-Level Laser Therapy, it is first important to understand their classification by the FDA:
- HLLT devices are classified as ‘Class IV Lasers’ by the FDA in virtue of having a power output that’s greater than 500mW (i.e. high risk of hazard). The vast majority of HLLT devices have longer near-infrared wavelengths.
- LLLT devices are classified as either ‘Class IIIB Lasers’, ‘Class IIIR Lasers’, or ‘Class II Lasers’ in virtue of having a power output of 5-500mW, 1-5mW, or <1mW respectively (i.e. lower risk of hazard). The vast majority of LLLT devices have shorter wavelengths.
There is a common misconception, often propagated by the manufacturers of Class 4 Lasers, that high power with longer wavelengths results in:
- Deeper penetration, allowing for the treatment of a wider range of conditions.
- More efficacious results, due to the delivery of more energy into the cells.
This however, is not correct for the following well-documented reasons:
- Laser light with wavelengths exceeding 950nm is highly absorbed by water, preventing much of its energy from penetrating the dermis. This strong absorption can also cause localised heating, leading to discomfort or pain, which may restrict its therapeutic application.
- There is an optimal ‘dose’ of laser energy (typically 2-4 joules / cm²) required for therapeutic biostimulation. Deviating from this dose, either by providing significantly less or more energy, can be counterproductive. HLLT devices, with their substantial power outputs, risk surpassing this optimal range.
- It is theorised that a minimum energy of 1.7eV per photon is required for therapeutic biostimulation via photochemical means – wavelengths exceeding 730nm cannot deliver this 1.7eV. As a result, HLLT devices, which often operate within these longer wavelengths, may not primarily function through inducing photochemical reactions. Instead, they might rely on alternative mechanisms, such as the therapeutic influence of localised heat generation. However, this approach may be less efficacious compared to biostimulation by photochemistry.
Low-Level Laser Therapy devices, on the other hand, aim to deliver energy via low output, short wavelength beams of light. The general theory is that this approach transfers the optimal amount of energy for stimulating and enhancing cell function, while not damaging cells or producing painful heat sensations.
Within the LLLT sector however, some of the higher output devices still generate heat / pain. Furthermore, many devices are advertised as ‘lasers’, when in fact they are Light Emitting Diodes (LEDs) or Superluminescent Diodes (SLDs). In contrast to LEDs or SLDs, ‘true’ lasers generate monochromatic, collimated, and coherent beams of light. These three properties of true lasers make them the most effective and efficient devices within Laser Therapy.
To separate Erchonia® from such technologies, and from HLLT more generally, we say that Erchonia® lasers are ‘non-thermal, true lasers’. That is, our lasers do not produce any heat or painful sensations, and are monochromatic, collimated, and coherent.
What Are the Best Low-Level Laser Therapy (LLLT) Devices on the Market Today?
Several companies manufacture Low-Level Laser Therapy devices, each offering different approaches to pain management, fat reduction, and tissue repair. Choosing the right LLLT device depends on factors such as wavelength, clinical evidence, and treatment goals. Some of the leading brands include:
- Erchonia® – The global leader in non-thermal, true laser technology, holding 22 of the 25 FDA clearances granted for Low-Level Lasers, including approvals for pain management, fat loss, and fungal nail treatment.
- Multi Radiance Medical – Focuses on super pulsed laser technology for pain relief and rehabilitation.
- THOR Photomedicine – Specialises in red and near-infrared LED and laser therapy for clinical applications.
- Aspen Laser Systems – Provides high-powered laser therapy devices aimed at pain relief and tissue healing.
- LiteCure (now part of DJO Global) – Offers Class IV lasers for musculoskeletal pain and rehabilitation.
How Does Erchonia® Stand Out from the Competition?
Erchonia® sets itself apart with true non-thermal lasers backed by gold-standard clinical research on LLLT. Unlike many competitors that use high-powered Class IV lasers, which can generate heat and risk tissue damage, our devices use precise wavelengths and low power over time to stimulate cellular repair without producing heat.
Additionally, Erchonia®:
- Holds 22 out of 25 FDA market clearances for Low-Level Laser Therapy applications.
- Uses collimated, coherent, and monochromatic laser diodes—not LEDs—for optimal penetration and efficacy.
- Is the only company with FDA-cleared devices for fat reduction (Emerald® Laser), fungal nail treatment (Lunula® Laser), and multiple pain management applications (EVRL®, FX635, GVL).
- Innovates with multi-wavelength technology (red, green, and violet lasers) to target specific mitochondrial complexes for maximum therapeutic benefit.
For scientifically validated, effective, and non-invasive LLLT technology, Erchonia® is the clear choice.
Ready to Take the Next Step?
- Patients: Use our Provider Locator to find a trusted Erchonia® laser specialist near you and start your treatment journey today.
- Clinics & Practitioners: Talk with our team about integrating Erchonia® lasers into your clinic and see how non-thermal LLLT can boost outcomes—and your bottom line.
▶︎ Find a Provider | ▶︎ Grow My Clinic – Contact Us
Common FAQs
What Are All of the Conditions That Low-Level Laser Therapy Is Used to Treat?
Low-Level Laser Therapy is often employed in the cosmetic and medical industries to treat the following conditions:
Pain Relief:
- Chronic pain conditions (e.g., arthritis, back pain)
- Acute pain from injuries
- Neuropathic pain
Wound Healing:
- Post-surgical wounds
- Diabetic ulcers
- Pressure sores
Inflammation Reduction:
- Inflammatory conditions (e.g., tendinitis, bursitis)
- Joint inflammation
Muscle and Joint Conditions:
- Muscle strains and sprains
- Joint disorders (e.g., temporomandibular joint disorder)
Skin Conditions:
- Acne
- Psoriasis
- Eczema
- Rosacea
Hair Regrowth:
- Androgenetic alopecia (male and female pattern baldness)
- Alopecia areata
Nerve Regeneration:
- Peripheral neuropathy
- Carpal tunnel syndrome
Dental Applications:
- Oral mucositis
- Cold sores
- Tooth sensitivity
- Periodontal disease
Rehabilitation and Recovery:
- Post-exercise muscle recovery
- Recovery from sports injuries
Fat Reduction and Body Contouring:
- Non-invasive body sculpting
- Reduction of localised fat
- Weight loss / full-body fat loss
Fungal Nail Treatment:
- Onychomycosis (fungal nail infection)
Other Medical Conditions:
- Fibromyalgia
- Lymphedema
- Rheumatoid arthritis
Is Low-Level Laser Therapy FDA Approved?
Yes, Low-Level Laser Therapy is FDA approved for various applications. Devices such as the Erchonia EVRL® Laser have received FDA market clearance for treating chronic and acute back, neck, and shoulder pain, as well as pain associated with surgery. Additionally, Erchonia’s Emerald® Laser is FDA-cleared for body circumference reduction, and the Lunula® Laser is FDA-cleared for the treatment of fungal nail infections.
How Does Low-Level Laser Therapy Benefit Hair?
Low-Level Laser Therapy stimulates cellular activity within hair follicles, leading to various positive outcomes for hair growth and overall hair quality. Below is a summary of the benefits of LLLT for hair health, along with the hypothesised mechanism of action.
1. Stimulates Hair Follicle Growth
LLLT penetrates the scalp and stimulates the hair follicles at a cellular level. The light energy is absorbed by the cells which helps to increase the production of adenosine triphosphate (ATP). This boost in cellular energy enhances follicle function and promotes the growth phase (anagen phase) of the hair cycle, leading to increased hair growth.
2. Increases Blood Flow to the Scalp
LLLT improves blood circulation in the scalp. The enhanced blood flow ensures that hair follicles receive more oxygen and essential nutrients, which are crucial for healthy hair growth. Improved circulation also helps to remove waste products from the scalp, creating a healthier environment for hair to grow.
3. Reduces Inflammation and Promotes Healing
Inflammation in the scalp can inhibit hair growth and contribute to hair loss. LLLT has anti-inflammatory effects that reduce inflammation and promote healing. This therapeutic effect helps to create a more conducive environment for healthy hair development.
4. Strengthens Hair Follicles
The increased ATP production and improved blood flow strengthen hair follicles, making them more resilient. Stronger hair follicles are less likely to shed prematurely and are better equipped to produce thicker, healthier hair strands.
5. Enhances Hair Density and Thickness
Regular LLLT treatments have been shown to increase the density and thickness of hair. By stimulating dormant hair follicles and promoting new hair growth, LLLT can lead to fuller and thicker hair over time.
6. Slows Down Hair Loss
LLLT helps to slow down the progression of hair loss by prolonging the anagen phase of the hair cycle and delaying the onset of the shedding phase (telogen phase). This effect helps to maintain a higher volume of hair and reduce overall hair loss.
7. Enhances the Efficacy of Other Treatments
LLLT can be used in conjunction with other hair loss treatments such as topical minoxidil, oral finasteride, or platelet-rich plasma (PRP) therapy. Combining LLLT with these treatments can enhance their efficacy and provide more comprehensive results.
8. Suitable for Various Hair Types and Conditions
LLLT is very versatile and can be used for various hair types and conditions. Whether you are experiencing genetic hair loss (androgenetic alopecia), thinning hair, or hair loss due to other factors, LLLT can be an effective component of your hair care regimen.
What Are the Biological Effects of Low-Level Laser Therapy?
Clinical studies suggest that Low-Level Laser Therapy has numerous biological effects – several prevailing theories are outlined below.
- Anti-Inflammation: LLLT creates an anti-edema effect by dilating blood vessels and activating the lymphatic drainage system (which drains swollen areas). This reduces swelling caused by trauma or inflammation.
- Anti-Pain (Analgesic): LLLT exerts a very beneficial effect on pain in multiple ways: It partially blocks neural transmission of pain signals to the brain; It decreases nerve sensitivity; It lessens pain by reducing edema; It helps to increase the production of high levels of painkilling chemicals such as endorphins, enkephalins, and opioids from the brain and adrenal gland.
- Accelerated Tissue Repair and Cell Growth: Photons of light from lasers penetrate deeply into tissues and accelerate cellular reproduction and growth. The laser light also increases the energy available to the cell by increasing ATP production so that the cell can take on nutrients faster and get rid of waste products. As a result of exposure to laser light, all cells, including the cells of tendons, ligaments, and muscles, are repaired faster.
- Improved Vascular Activity: LLLT significantly increases the formation of new capillaries in damaged tissue, which speeds up the healing process, closes wounds more quickly, and reduces scarring. LLLT also causes vasodilation – an increase in the diameter of blood vessels – which improves the delivery of blood and healing elements to damaged tissues.
- Increased Metabolic Activity: LLLT stimulates higher outputs of specific pro-healing enzymes in blood cells, along with improved oxygen and nutrient delivery.
- Trigger Points and Acupuncture Points: LLLT stimulates muscle trigger points and acupuncture points on a non-invasive basis, providing musculoskeletal pain relief.
- Reduced Fibrous Tissue Formation: LLLT reduces the formation of scar tissue following damage from cuts, scratches, burns, or surgery.
- Improved Nerve Function: Slow recovery of nerves in damaged tissue results in impaired sensory and motor function. LLLT speeds up the process of axonal regeneration and nerve cell reconnection, and increases the amplitude of action potentials to optimise muscle action.
- Immunoregulation: LLLT directly affects immunity status by stimulating the production of immunoglobulins and lymphocytes, and by improving the ease of penetration of white blood cells into damaged tissue.
- Faster Wound Healing: LLLT stimulates fibroblast development in damaged tissue. Fibroblasts are the building blocks of collagen, which is the essential protein required to replace old tissue or repair tissue injuries. As a result, LLLT is effective on open wounds and burns.
How Do Different Wavelengths Affect Treatment Outcomes?
The effectiveness of Low-Level Laser Therapy depends on the specific wavelength used. Each wavelength interacts with cellular structures differently, targeting mitochondrial complexes to enhance energy production, reduce inflammation, promote healing, and address specific conditions.
- Red Light (e.g. 635nm) – Pain Relief, Tissue Repair & Nail Fungus Treatment: Red light is optimal for stimulating Complex IV of the electron transport chain, enhancing ATP (cellular energy) production. This leads to accelerated tissue repair, reduced inflammation, and improved immune function via increased Interleukin-10 (IL-10). It is widely used for musculoskeletal pain relief, wound healing, and nerve regeneration. Additionally, red light plays a role in treating fungal nail infections, working in combination with violet light to promote an antifungal response.
- Green Light (e.g. 520nm) – Fat Loss, Collagen Production & Cellular Regeneration: Green light uniquely stimulates Complex III, supporting stem cell activation, collagen synthesis, and chondrocyte function. It has been FDA-cleared for pain and inflammation reduction and is particularly effective in fat loss treatments. The current theory also suggests that green light helps create transient pores in fat cells (adipocytes), allowing lipids to be released and metabolised naturally through the lymphatic system. Unlike fat freezing techniques that eliminate fat cells, green laser therapy encourages them to function like healthy, lean cells, restoring proper metabolic signalling.
- Violet Light (e.g. 405nm) – Antimicrobial, Scar Tissue Repair & Nail Fungus Treatment: Violet light has the highest photon energy per wavelength, making it uniquely effective for Complexes I and II of the mitochondria. It is particularly valuable for antimicrobial applications, helping to combat bacteria, fungi, and viruses. When used alongside red light, violet laser therapy enhances the body’s natural antifungal response by generating Reactive Oxygen Species (ROS) that convert into hydrogen peroxide, a natural antiseptic that kills fungal infections. This makes it an ideal treatment for onychomycosis (fungal nail infections).
- Combining Wavelengths for Enhanced Results: By combining red, green, and violet wavelengths, treatments can target multiple biological pathways, improving pain relief, fat metabolism, immune response, and tissue regeneration. Clinical research has demonstrated that using a combination of these wavelengths leads to superior results compared to single-wavelength treatments.
For optimal therapeutic outcomes, selecting the right wavelength—or a combination—is key.
When Will I See Results?
The timeline for results varies depending on the condition being treated. For example, some patients experience pain relief after just a few sessions, while improvements in skin conditions or hair regrowth may take several weeks. Consistency with treatments is key for optimal results.
How Long Do the Results Last?
The duration of the results from Low-Level Laser Therapy can vary significantly based on the condition treated, the individual patient, and adherence to follow-up care – generally, the beneficial effects can last for several weeks to several months. For chronic conditions like arthritis or musculoskeletal pain, patients might experience relief for several months after a full course of treatment. However, maintenance sessions may be recommended to sustain the results. For cosmetic treatments, such as fat reduction or skin rejuvenation, results can be long-term if accompanied by a healthy lifestyle. Regular follow-up sessions might be necessary to maintain optimal results.
Are There Any Conditions Which Would Prevent Patients From Receiving the Treatments?
There are no code regulated contraindications, however, since there are no long-term evaluations on certain conditions, it is not recommend to use Low-Level Laser Therapy on pregnant women, clients with a pacemaker, or clients with photosensitive epilepsy. It is also advised to not use LLLT over an area of known cancer.
Does Low-Level Laser Therapy Hurt?
No, Low-Level Laser Therapy is completely painless. Patients may experience a mild warming sensation due to increased blood flow, but there is no discomfort or downtime.
Is There Any Downtime After Low-Level Laser Therapy?
No, there is no downtime. Patients can resume normal activities immediately after treatment.
How Long Is a Treatment?
A typical Low-Level Laser Therapy treatment lasts between 5 to 30 minutes. The exact length depends on the condition being treated and the specific protocol being followed. For example, treatments for chronic pain might be shorter (around 5-10 minutes per session), whereas treatments for more extensive tissue repair or fat reduction could be longer (up to 30 minutes).
How Often Should You Use Low-Level Laser Therapy?
The frequency of using Low-Level Laser Therapy depends on the condition being treated, its severity, and the patient’s response to therapy. For instance, for acute conditions like recent injuries or surgical recovery, LLLT may be applied more regularly – daily or every other day for 1-2 weeks. Chronic conditions, such as arthritis or neuropathic pain, may require less frequent treatments, ranging from 2-3 times a week to once a week for several weeks or months.
The general approach is to monitor the patient’s progress and adjust the treatment schedule based on their response. The therapy sessions themselves typically last from a few minutes to half an hour, depending on the area being treated and the device used. Erchonia’s lasers, for example, are non-thermal and can be used consistently without causing heat-related side effects, allowing for regular, safe usage.
Can Low-Level Laser Therapy Be Combined with Other Treatments?
Yes, Low-Level Laser Therapy is often used alongside other treatments to enhance results. It can complement procedures such as microneedling, PRP therapy, injectables, and post-surgical recovery by reducing inflammation and accelerating healing.
Can Low-Level Lasers Damage Eyes?
Yes, Low-Level Lasers can potentially damage the eyes if proper precautions are not taken – prolonged exposure to laser light can harm the retina and cause damage. To ensure safety and prevent any accidental exposure, practitioners and patients should always wear protective eyewear during the treatment.
What Is the Difference Between Laser and Low-Level Laser Therapy?
The key difference between “laser” and “Low-Level Laser Therapy” lies in their power, purpose, and physiological effects:
- Laser: The term “laser” broadly refers to a device that emits light through optical amplification. Depending on the power output, lasers can range from low-power (used in LLLT) to high-power devices used in surgeries. High-Level Lasers, classified as Class IV by the FDA, typically have a power output greater than 500mW and can generate heat. These lasers are often used for cutting, cauterising, or ablating tissue in surgical procedures, and they work by heating and destroying cells, making them ideal for medical or cosmetic surgery.
- Low-Level Laser Therapy: LLLT uses lasers with much lower power outputs (less than 500mW). These low-power lasers are designed specifically for therapeutic purposes, stimulating cellular function without generating heat. LLLT works by promoting cell regeneration, reducing inflammation, and enhancing tissue repair through photochemical reactions. It is non-invasive, painless, and does not cause thermal damage, making it safe for repeated use in conditions like chronic pain, musculoskeletal issues, and wound healing.
In summary, while both use laser technology, High-Level Lasers should primarily be used for their thermal and destructive capabilities in surgery, while LLLT harnesses low-power, non-thermal lasers for therapeutic purposes, focusing on healing and cellular stimulation without tissue damage.
Is Low-Level Laser Therapy the Same as Led?
No, Low-Level Laser Therapy is not the same as LED (Light Emitting Diode) therapy, although both involve light-based treatments.
- Laser: True lasers, as used in LLLT, produce light that is monochromatic (single wavelength), collimated (light beams are parallel), and coherent (waves of light are in phase). These qualities allow laser light to penetrate tissues more efficiently and target specific cellular processes with precision. This focused energy makes LLLT especially effective at stimulating mitochondrial activity, accelerating healing, and reducing pain.
- LED: LED devices emit non-coherent light, which means the light waves are not in phase, and the beams are more diffuse. While LED therapy can be beneficial for superficial treatments, such as enhancing skin health, it is generally less effective for deeper tissue treatments or conditions that require more focused cellular stimulation. LED lights also do not penetrate as deeply as lasers, reducing their efficacy in comparison to LLLT for conditions like chronic pain or inflammation.
In short, while both modalities use light, LLLT is more potent and precise due to its laser properties, making it more effective for a wider range of medical applications.
What Is Another Name for Low-Level Laser Therapy?
Low-Level Laser Therapy is known by several names, reflecting its different applications and the evolution of research in the field. It is also referred to as:
- Non-Thermal Laser Therapy – emphasising its ability to deliver therapeutic effects without generating heat.
- Cold Laser Therapy – highlighting its non-invasive, low-power nature.
- Photobiomodulation (PBM) Therapy – describing its role in stimulating cellular processes using light.
- Low-Power Laser Therapy (LPLT) – indicating its gentle, controlled energy output.
- Soft Laser Therapy – another term used to describe its non-thermal effects.
- Low-Intensity Laser Therapy (LILT) and Low-Energy Laser Therapy – referring to its targeted, low-dose energy application.
- Bio-Stimulation Laser Therapy and Photo-Biotherapy – focusing on its ability to enhance cellular function and healing.
- Therapeutic Laser – a general term used in clinical settings.
- Monochromatic Infrared Light Energy (MIRE) Therapy – a more technical classification based on wavelength properties.
Specific applications of LLLT have their own terms. When applied to acupuncture points, it is known as laser acupuncture. When used for brain-related therapies, it may be called transcranial photobiomodulation, transcranial near-infrared laser therapy (NILT), or transcranial low-level light therapy.
All these terms describe the same fundamental technology: a safe, effective, and clinically supported laser therapy designed to promote healing, reduce pain, and enhance cellular function without thermal damage.
What Is the Scientific Evidence Behind Erchonia® Lasers?
All studies carried out to obtain FDA-clearance are double blind, randomised, placebo-controlled, and multi-site – the most credible research of all Laser Therapy devices on the market today.
The following list shows the clinical trials and an outline of their progress. As a company, to protect our intellectual assets, not all clinical trials we are involved with are made public so as to maintain our competitive advantage. As such, not all clinical trials are listed below.
Please note: There are hundreds of clinical studies confirming the effectiveness of Low-Level Laser Therapy, and every year there are many new publications. Below is a list of Erchonia-specific studies for FDA-clearance.
1) Chronic Neck and Shoulder Pain / Low Level Laser — 2000 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- First study done in support of 510(k) submission, second study requested by FDA.
2) Chronic Neck and Shoulder Pain / Low Level Laser — 2001 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- Study results used to obtain FDA clearance – K012580
- To view NIH clinical trial records, click here.
3) Low Level Laser Light Therapy as an Aid to Liposuction and Reduction of Pain Associated With Surgery — 2004 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- Study results used to obtain FDA clearance – K041139
- To view NIH clinical trial records, click here.
4) Acne Vulgaris — Dermatological Conditions / Low Level Laser — 2005 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- FDA clearance – K050672
5) Pain Associated With Breast Augmentation Surgery / Low Level Laser — 2007 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- Results used to obtain FDA clearance – K072206
- To view NIH clinical trial records, click here.
6) Non-Invasive Fat Reduction and Body Contouring – Laser Scanner Waist, Hips, and Thighs — 2009 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- Study results used to obtain FDA clearance – K082609
- To view NIH clinical trial records, click here.
7) Equine Wound Healing – 2011 — Sponsor, Case Study.
- Study completed from Nov. 2010-March 2011.
- Monitored by Hank Jann, DVM, MS, DACVS from Oklahoma State University.
8) Equine Wound Healing – 2011 — Sponsor, placebo controlled, clinical study.
- Study completed from Feb. 2011-April 2011.
- Monitored by Hank Jann, DVM, MS, DAVCS from Oklahoma State University.
9) Arm Circumference Reduction of the Upper Arms — 2011 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- Study results used to obtain FDA clearance – K120257
- Study submitted to be published 2012.
- To view NIH clinical trial records, click here.
10) Appearance of Cellulite (Verju Laser System) — 2012 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- FDA clearance – K130922
- Study submitted to be published 2013.
- To view NIH clinical trial records, click here.
11) Non-Invasive Body Contouring Using GLS Laser – 532 nm (Green) Trade Name Verju — 2012 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- FDA clearance – K123237
- Study submitted to be published 2013.
- To view NIH clinical trial records, click here.
12) Adjunct to Chronic Heel Pain Arising from Plantar Fasciitis Using the Erchonia FX635 Laser — 2012 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- FDA clearance – K132940
- Study results published in the American Orthopaedic Foot & Ankle Society April 2014
- To view NIH clinical trial records, click here.
13) Non-Invasive Dermatological Aesthetic Treatment for Reduction of Circumference of Hips, Waist and Upper Abdomen When Applied to Individuals with a Body Mass Index (BMI) Between 30 kg/m2 and 40 kg/m2 — 2013 – Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- FDA clearance – K142042
- To view NIH clinical trial records, click here.
14) Non-Invasive Dermatological Aesthetic Treatment for the Reduction of Circumference of Hips, Waist and Thighs (Zerona-Z6 OTC) — 2012 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- FDA clearance – K143007
- To view NIH clinical trial records, click here.
15) Non-Invasive Dermatological Aesthetic Treatment for the Reduction of Circumference of Hips, Waist, Thighs and Upper Abdomen — 6 Week Treatment Protocol (Zerona-Z6) — 2014 — Sponsor and monitor, IRB approved, double blind, placebo controlled, multi-site, clinical study.
- FDA clearance – K150446
- To view NIH clinical trial records, click here.
16) Erchonia EVRL (EVRL) – 2016
a. while using the red diode, for adjunctive use in providing temporary relief of minor chronic neck and shoulder pain of musculoskeletal origin.
b. and while using the violet diode, to treat dermatological conditions, and specifically indicated to treat moderate inflammatory Acne Vulgaris.
- FDA clearance – K152196
17) Temporary Increase of Clear Nail in Patients With Onychomycosis (e.g., Dermatophytes Trichophyton Rubrum and T. mentagrophytes, and/or Yeasts Candida Albicans, etc.) (Lunula Laser ) — 2016 — Sponsor and monitor, IRB approved, blind, placebo controlled, clinical study.
- FDA clearance – K153164
- To view NIH clinical trial records, click here.
18) Non-Invasive Dermatological Aesthetic Treatment for the Reduction of Body Circumference (Zerona-Z6) — 2016.
- FDA clearance – K162578
19) Market Clearance to Treat Chronic Low Back Pain (FX 635) — 2018 — Placebo-controlled, randomized, double-blind, parallel-group, multi-center clinical study.
- FDA clearance – K180197
- To view NIH clinical trial records, click here.
20) Market Clearance for Relief of Chronic Musculoskeletal Pain (FX 635) — 2019 — A collection of placebo-controlled, randomized, double-blind, parallel-group, multi-center clinical studies.
- FDA clearance – K190572
21) Non-Invasive Dermatological Aesthetic Treatment for the Reduction of Body Circumference in Individuals With a Body Mass Index (BMI) of up to 40 kg / m² — 2019 — The data used to get this approval combined all previous data Erchonia® had on 20-40 BMI patients in the green laser studies above.
What Is the Difference Between Erchonia® and Other Technologies in This Market?
The efficacy of Erchonia® lasers has been scientifically proven with double blind, randomised, placebo-controlled, and multi-site studies. Many competing companies advertise their products as ‘clinically proven’, guaranteeing ‘instant results’. However, these claims are often not backed by comprehensive clinical evidence.
Several companies have FDA-clearance within the Laser Therapy sector, however, in most cases the intended use / indications of their products are quite limiting or not relevant to the marketed applications. Furthermore, these FDA-clearances are often obtained without any scientific research.
We always recommend that you ask for details of the FDA-clearances and make an informed decision. Pay particular attention to the scope of the clearance, whether it involved clinical studies, how many patients participated, were the studies placebo controlled, double blind, and randomised, how many peer reviewed published articles they have, and what the adverse reactions / side effects were – we would be happy to provide this information for you.
What Conditions Can Erchonia® Pain Relief Lasers Help With?
Erchonia® pain relief lasers can help a wide variety of patients, including: Orthopaedic pain – sprains, whiplash, muscular pain, cervical or lumbar radiculopathy, tendinitis, and carpal tunnel syndrome. Our devices have also shown positive effects on individuals with chronic conditions like arthritis and osteoarthritis, and in treating post-surgical pain; Neuropathic pain, including various types of neuralgia and diabetic neuropathy; Pain management for athletes recovering from training or injuries.
What Areas Do Erchonia® Fat Removal Lasers Treat?
Erchonia® lasers for fat removal treat overall body circumference while also allowing patients to target stubborn areas of fat and cellulite.
Most people who undergo the treatments focus on their midriff and thighs, but the device can also target any area of subcutaneous fat, including bra strap, upper arms, jowls, knees, and more.
Will Erchonia® Lasers Cause Pain or Burning?
Erchonia® are true non-thermal Low-Level Laser Therapy devices and cause no pain or health risks.
What Do Erchonia® Lasers Treat and How Are They Used?
Erchonia® lasers are used in many areas, such as 360-degree fat loss, body sculpting, cellulite reduction, pain management, pre / postsurgical healing, pre / rehabilitation, nail and skin pathologies (e.g. nail fungus and acne), and more.
The most effective, medical-grade devices for pain relief include XLR8®, EVRL®, GVL®, FX635®, FX405®, and Base Station. For fat reduction and body contouring, Emerald™, Verjú®, and VZ8 deliver exceptional results. The Lunula® Laser stands out as the only fully automated LLLT device FDA-cleared for fungal nail treatment. Each device is backed by robust clinical research and FDA clearances, ensuring the highest level of safety and efficacy.
Why Choose Erchonia®?
With over 25 years of experience, 18,000+ devices in the market, and 22 FDA-clearances, Erchonia® Corporation are world leaders in medical-grade Laser Therapy technology.
Erchonia® own 22 of the 25 FDA-clearances given to Low-Level Laser Therapy devices, and the efficacy of our machines has been proven by multiple (level 1) double blind, randomised, placebo-controlled, and multi-site clinical studies – the most credible research in the market today.
We are dedicated to producing safe, effective solutions designed for physicians, chiropractors, physical therapists, podiatrists, osteopaths, aesthetics clinics, veterinarians, and many other types of medical / health professionals.
All Erchonia® laser systems are cut from raw materials, and all of our products go through a rigorous quality control process before delivery to our customers around the world. As a company, we are 85% self-reliant in all facets of our organisation, and all of our products are FDA, ISO, OSHA, and MDSAP compliant.
The Erchonia® mission statement is simply “Quality Not Compromise”, and this is ingrained in every aspect of our business – from an unwavering belief in the limitless potential applications of Low-Level Lasers, down to the care and quality of the smallest component of our devices. Just pick up any Erchonia® product, feel the quality of workmanship, and see the attention to detail that can only come from Erchonia’s near-complete control of the manufacturing and assembly processes that go into each product bearing the Erchonia® name. Read More
Would like to know if a hand held laser can be rented.
Hi Natasha, a member of our team will get back to you ASAP with the details.
Where would be the best place to purchase your product and which is the best all round device
Hi Linda, thank you for your message. A member of our team will get back to you ASAP.
I’m looking for a LLLT for my wife, she has neuropathy and was told this could help with cell and tissue damage. Can you recommend which device would be best for her to use on her feet?
Hi Randy, thank you for your message. A member of our team will get back to you ASAP.